Comparison of Pregabalin with Pramipexole for Restless Legs Syndrome
نویسندگان
چکیده
منابع مشابه
Long-term treatment with pramipexole in restless legs syndrome.
The aim of the present study was to look at the long-term efficacy and side effects profiles of pramipexole in a large cohort of drug naïve patients with regard to dopaminergic medications. In all, 195 consecutive restless legs syndrome (RLS) patients who were prescribed pramipexole more than 1 year previously, agreed to undergo a telephone interview to assess both the efficacy and side effects...
متن کاملPregabalin versus pramipexole: effects on sleep disturbance in restless legs syndrome.
STUDY OBJECTIVES To compare pregabalin versus placebo and pramipexole for reducing restless legs syndrome (RLS)-related sleep disturbance. DESIGN Randomized, double-blinded, crossover trial. SETTING Twenty-three US sleep centers. PARTICIPANTS Eighty-five individuals with moderate to severe idiopathic RLS and associated sleep disturbance. INTERVENTIONS Participants were randomized across...
متن کاملRestless legs syndrome: differential diagnosis and management with pramipexole
Restless legs syndrome (RLS) is a condition characterized by discomfort at rest and urge to move focused on the legs. RLS may occur as an idiopathic, often hereditary condition (primary RLS), or in association with medical conditions (secondary RLS) including iron deficiency, uremia, and polyneuropathy. Current understanding of the pathophysiology of RLS points to the involvement of three inter...
متن کاملfactors affecting the efficacy of pramipexole in patients with restless legs syndrome.
dopamine agonists, particularly nonergot dopamine agonists such as pramipexole, have become the mainstay of therapy for patients with symptoms of restless legs syndrome (rls). this study was designed to evaluate the factors affecting the efficacy of pramipexole in patients with rls. fifty-nine eligible rls patients referred to neurology clinic of rasoul-e-akram hospital (tehran, iran) were recr...
متن کاملPramipexole: new use for an old drug – the potential use of pramipexole in the treatment of restless legs syndrome
Restless legs syndrome (RLS) is characterized by paraesthesias-dysesthesias and motor restlessness worsening at rest-in the evening, with at least temporary relief by activity. Its etiology is unknown, though it could be secondary to various conditions. It is well known, however, that dopamine plays a crucial role in the pathophysiology of RLS, as dopaminergic agonists achieve marked improvemen...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 2014
ISSN: 0741-5214
DOI: 10.1016/j.jvs.2014.04.024